Wellness for Life Blog | Does Weed Give You Acne? ome users notice breakouts after using weed. While not everyone reacts the same, marijuana may trigger hormonal shifts or skin inflammation. If you're seeing pimples or clogged pores, weed might be playing a role. We break down the science, risks, and prevention strategies. Wellness for Life Blog gives you skin health facts you can trust. Click now to explore the real connection between cannabis and acne.